Publications

McAdams H. H. and G. K. Walters, "Dynamic polarization of liquid helium three," Phys. Rev. Lett., 18(12), 436 (1967)

McAdams, H. H., "New liquid ⁴He Experimental cryostat," Rev. Sci. Instr., 39(1) (1968)

McAdams, H. H. and G. K. Walters, “Dynamic Nuclear Polarization of Liquid Helium-Three by Optical Pumping,” Phys. Rev. (USA) 170(1) 276-285 (1968)

McAdams, H. H. and L. Shapiro, “Circuit Simulation of Genetic Networks,” Science, 269, 650-656 (1995) [PDF]

McAdams, H. H. and A. Arkin, "Stochastic mechanisms in gene expression,” Proc. Nat. Acad. Sci., USA, 94, 814-19 (1997) [PDF]

McAdams, H. H. and A. Arkin, “Simulation of Prokaryotic Genetic Circuits,” Ann. Rev. Biophys. Biom. Struct., 27,  199-224 (1998) [PDF]

Arkin, A., Ross, J., McAdams, H. H., "Stochastic kinetic analysis of developmental pathway bifurcation in phage l-infected E. coli cells," Genetics, 149, 1633-1648 (1998) [PDF]

Hung, D., McAdams, H. H., Shapiro, L.  "Regulation of the Caulobacter Cell Cycle". In Microbial Development, ed. Y. Brun, L. Shimkets. Washington, DC: ASM Press, (1999)

McAdams, H. H. and A. Arkin, "It's a noisy business!  Genetic regulation at the nanomolar scale,” Trends in Genetics. 15:65-69 (1999) [PDF]

McAdams, H. H. and A. Arkin, "Genetic regulatory circuits: Advances toward a genetic circuit engineering discipline".  Current Biology, 10:318-320 (2000) [PDF]

Judd, E. M., M. T. Laub, H. H. McAdams, "Toggles and oscillators: New genetic circuit designs".  BioEssays.  22:507-509 (2000) [PDF]

Laub, M. T., H. H. McAdams, T. Feldblyum, C. M. Fraser, L. Shapiro, "Global analysis of the genetic network controlling a bacterial cell cycle".  Science.  290:2144-2148 (2000) [PDF]

Michael T. Laub, Lucy Shapiro, Harley H. McAdams, “Global Approaches to the Bacterial Cell as an Integrated System” in The Bacterial Chromosome, Ed. N. Patrick Higgins.  ASM Press, Washington DC.  In press.

Laub, M. T., Chen, S. L., Shapiro, L., McAdams, H. H., “Genes directly controlled by CtrA, a master regulator of the Caulobacter cell cycle,” Proc. Nat. Acad. Sci., USA. 99(7):4632-7 (2002) [PDF]

Shapiro, L., McAdams, H. H., Losick R.  "Generating and exploiting polarity in bacteria"  Science, 298(5600):1942-6. (2002) [PDF]

Judd, E. M., Ryan, R. R., Moerner, W. E., Shapiro, L., McAdams, H. H.  "Fluorescence bleaching reveals asymmetric compartment formation prior to cell division in Caulobacter"  Proc. Nat. Acad. Sci., USA., 100(14):8235-8240 (2003) [PDF]

McAdams, H. H. and L. Shapiro, "A bacterial cell-cycle regulatory network operating in time and space"  Science 301(5641):1874-7 (2003) [PDF]

McAdams, H. H., Srinivasan, B., Arkin, A. P. “Evolution of Bacterial Regulatory Networks”, Nature Reviews Genetics. 5(3):169-178 (2004)

McGrath, P. T., Viollier, P., McAdams, H. H. “Setting the Pace: Mechanisms tying Caulobacter cell-cycle progression to macroscopic cellular events”, Current Opinion in Microbiology.  7(2):192-7 (2004)

Chen, S. L., Lee, W., Hottes, A. K., Shapiro, L., McAdams, H. H.  “Evidence that genome-wide codon usage is driven by mutation”  Proc Nat Acad Sci (USA).  101(10):3480-5 (2004)

Hottes, A. K., Meewan, M., Yang, D., Arana, N., Romero, P., McAdams, H. H., Stephens, C.  “Transcriptional profiling of Caulobacter crescentus during growth on complex and minimal media”  J. Bacteriology.  186(5):1448-1461 (2004)

Holtzendorff, J., Hung, D., Brende, P., Reisenauer, A., Viollier, P., McAdams, H. H., Shapiro, L. “Oscillating global regulators control the genetic circuit driving a bacterial cell cycle” Science.  304(5673):983-7 (2004)

Viollier, P. H., Thanbichler, M., McGrath, P. T., West, L., Meewan, M., McAdams, H. H., Shapiro, L.  “Rapid and sequential movement of individual chromosome loci to specific subcellular locations during bacterial DNA replication.”  Proceedings of National Academy.  101(25):9257-62 (2004)

Deich J, Judd EM, McAdams HH, Moerner WE. “Visualization of the movement of single histidine kinase molecules in live Caulobacter cells” Proc Natl Acad Sci USA. 101(45):15921-15926 (2004)

Crosson S.,  McAdams HH, Shapiro L. “A genetic oscillator and the regulation of cell cycle progression in Caulobacter crescentus” Cell Cycle 3:10 e5-e57 [2004]

Viollier, P.H., M. Thanbichler, P. McGrath, L. West, M. Meewan, H.H. McAdams, L. Shapiro.  "Rapid and sequential movement of individual chromosomal loci to specific subcellular locations during bacterial DNA replication".  Proc Natl Acad Sci U S A 101:9257-9262 (2004)

Crosson S., McGrath P.T, Stephens C., McAdams H. H., Shapiro L. “Conserved modular design of an oxygen sensory/signaling network with species-specific output” Proc Natl Acad Sci U S A 102(22):8018-23 (2005)

Judd E. M., Comolli L. R., Chen J. C., Downing K. H., Moerner W. E., McAdams H. H.  “Distinct constrictive processes, separated in time and space, divide Caulobacter inner and outer membranes” J. Bacteriology.  187(20):6874-82 (2005)

Hottes A. K., Shapiro L., McAdams H. H.  “DnaA coordinates replication initiation and cell cycle transcription in Caulobacter crescentus” Molecular Microbiology 58(5):1340–53 (2005)

Hu P., Brodie E. L., Suzuki Y., McAdams H. H., Andersen G. L. "Whole Genome Transcriptional Analysis of Heavy Metal Stresses in Caulobacter crescentus" J. Bact.  187(24):8437-8449  (2005)

Chen JC, Hottes AK, McAdams HH, McGrath PT, Viollier PH, Shapiro L.  “Cytokinesis signals truncation of the PodJ polarity factor by a cell cycle-regulated protease” EMBO J. 25(2):377-86(2006)

McGrath P., Iniesta A. A., Ryan K. R., Shapiro L., McAdams H. H. “A dynamically localized protease complex and a polar specificity factor control a cell cycle master regulator”  Cell.  124(3):535-47  (2006)

Srinivasan, B. S., A. F. Novak, J. A. Flannick, S. Batzoglou and H. H. McAdams. "Integrated Protein Interaction Networks for 230 Microbes"  BCATS 2005.

Srinivasan B, Novak A, Flannick J, Batzoglou S, McAdams H.  “Integrated Protein Interaction Networks for 11 Microbes”  Proceedings of the Tenth Annual International Conference on Computational Molecular Biology, (RECOMB 2006), pp. 1-14. (2006)

Flannick, J. A., A. F. Novak, B. S. Srinivasan, H. H. McAdams, S. Batzoglou, "Graemlin: General and robust alignment of multiple large interaction networks" Genome Research. In press (2006)